St Mary High School offers subjects to students including Technical Drawing, Building Technology, Industrial Technology, Mathematics, Physical Education, General Science, Social Studies, Home Economics, Biology, Geography, History, Physics, Food and Nutrition, Clothing and Textiles, Principles of Accounting, Office Administration, Principles of Business, English, Sociology, Music, Chemistry, Information Technology, Visual Art, Literature, Law, Spanish, Agricultural Science, and Religious Education and Extra-Curricular Activities.